Studies show that individuals on weekly GLP-1 injections on average (semaglutide and tirzepatide study numbers) after one year at the full-dose. Individual results do vary, and concurrent lifestyle modifications can have a big impact. Studies also indicate that a mere 5% reduction in weight can significantly enhance conditions such as hypertension, cholesterol levels, cardiovascular diseases, PCOS, osteoarthritis, and more. (Graph of relative weight loss drugs/exercise)